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A subset of these reports involved patients with renal insufficiency, some of whom were prescribed inappropriate doses of sitagliptin the dosing adjustment for januvia is necessary to achieve plasma concentrations of januvia similar to those patients with normal renal function lower doses of an insulin secretagogue or insulin may be required when coadministered with januvia to reduce the risk of hypoglycemia.

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Information about Januvia.

Your name may need to be listed on a Januvia pregnancy registry when you start using this medicine.

You should not use Januvia if you are in a state of diabetic ketoacidosiscall your doctor for treatment with insulin

Your doctor may prescribe JANUVIA alone or together with certain other diabetes medicines to help control blood sugarTake JANUVIA exactly as your doctor prescribes and follow your doctor’s treatment plan for healthy eating and exercise.

Your name may need to be listed on a Januvia pregnancy registry when you start using this medicine.

If you take JANUVIA with another medicine that can cause low blood sugarhypoglycemiasuch as a sulfonylurea or insulinyour risk of getting low blood sugar is higherThe dose of your sulfonylurea medicine or insulin may need to be lowered while you use JANUVIASigns and symptoms of low blood sugar may include headachedrowsinessweaknessdizzinessconfusionirritabilityhungerfast heart beatsweatingand feeling jittery.

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indeed, several of the newer drugs, such as januvia and onglyza, are less effective than the older medications.

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